Pancreatic Injury Repair & Fatty Pancreas Disease
Pancreatic Injury Repair & Fatty Pancreas Disease · School of Medicine, Yangzhou University
Welcome to Lu Lab
Lu Lab, led by Professor Guotao Lu at the School of Medicine, Yangzhou University, focuses on two core areas: pancreatic injury repair and Fatty Pancreas Disease (FPD), spanning the full spectrum from molecular mechanisms to clinical translation.
Centered on the two major clinical challenges of acute pancreatitis — "pancreatic necrosis" and "multiple organ failure" — the team systematically elucidates the pathological mechanisms of key cellular events including acinar cell necrosis, neutrophil extracellular traps (NETs), and macrophage efferocytosis, while advancing interventional translational research on inflammatory comorbidities (sepsis, rheumatoid arthritis, liver injury, intestinal injury, diabetic foot, etc.).
In the field of Fatty Pancreas Disease, the team has dedicated over a decade to elevating FPD from a vague imaging concept to an independent disease entity with clear definitions, diagnostic criteria, and intervention strategies, making it a core intervention point for the proactive prevention and control of major pancreatic diseases such as pancreatitis and pancreatic cancer, as well as metabolic diseases like diabetes.
Principal Investigator
Guotao Lu MD, PhD
Deputy Director, School of Medicine, Yangzhou University · Chief Physician · Doctoral Supervisor
Professor Lu is a National “Ten Thousand Talents Plan” Young Top-Notch Talent and a Jiangsu Outstanding Youth Fund recipient. He has led four NSFC grants and published over 40 high-impact papers as first/corresponding author in journals including Cell Rep Med, STTT, Gut, Mol Ther, Metabolism, Redox Biol, Adv Sci, and AJG. As a GARIF Expert Steering Committee member (one of only four globally), he co-led the 2026 Melbourne Consensus and chaired China’s first Fatty Pancreas Consensus.
Research
Innovative Targets for Pancreatic Injury Repair
Focusing on acinar cell necrosis, NETs, and macrophage efferocytosis to unravel the pathological mechanisms of acute pancreatitis and develop targeted therapies for inflammatory comorbidities.
Fatty Pancreas Disease: Intervention & Clinical Translation
Elevating FPD from a vague imaging concept to a clinically actionable disease entity through landmark epidemiological studies and global consensus leadership.
Research Grants
NSFC · Regional Joint Key Project
¥2.59M2026/01 – 2029/12 · PI
Jiangsu Outstanding Youth Fund
¥1.80M2024/09 – 2027/08 · PI
NSFC · General Program
¥0.52M2023/01 – 2026/12 · PI
NSFC · General Program
¥0.54M2021/01 – 2024/12 · PI
NSFC · Young Scientists Fund
¥0.22M2019/01 – 2021/12 · PI
Join Us
We are always looking for talented postdocs and PhD students. Interested candidates are welcome to reach out.
✉ gtlu@yzu.edu.cn